Evaluation of Hepatic Mitochondria and Hematological Parameters in Zidovudine-TreatedB6C3F1Mice
نویسندگان
چکیده
منابع مشابه
Evaluation of Hepatic Mitochondria and Hematological Parameters in Zidovudine-Treated B6C3F1 Mice
The effects of 12-week exposure to zidovudine (AZT) at 400, 500, and 600 mg/kg/d were examined on expression of 542 mitochondria-related genes and mitochondrial DNA (mtDNA) copy number in the liver of male and female B6C3F(1) mice to understand mitochondrial role in sex-related differences in development of lactic acidosis. Plasma lactate levels and hematologic parameters were also examined. Re...
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ژورنال
عنوان ژورنال: AIDS Research and Treatment
سال: 2012
ISSN: 2090-1240,2090-1259
DOI: 10.1155/2012/317695